EARLY VERSUS DELAYED INTERVENTION IN GASTRIC ADENOCARCINOMA - A RETROSPECTIVE STUDY

BUDISCA OVIDIU; Sohaib Ahmed; Ahsan Mushtaq; Nicolescu Cosmin; Florina-Maria  Gabor Harosa; Vladimir Vladimir Bacarea; Molnar Calin

doi:10.33695/rojes.v4i1.57

BUDISCA OVIDIU
Sohaib Ahmed
Ahsan Mushtaq
Nicolescu Cosmin
Florina-Maria Gabor Harosa
Vladimir Vladimir Bacarea
Molnar Calin

DOI: https://doi.org/10.33695/rojes.v4i1.57

Keywords: Emergency, Gastric Cancer, Adenocarcinoma, Early versus Delayed

Abstract

Aim: In the last decade, early intervention of gastric cancer had shown to leave an influence independent of other factors, on overall patient survival and outcome. The aim of our study is to evaluate the surgical outcomes by a comparison of diagnosed gastric cancer patients with an early interventional approach of 48 hours from admission compared with a delayed interventional approach.

Material & Method: An eight-year retrospective study comprising of 185 admissions was conducted in patients admitted at the 1st Department of Surgery, Clinical Emergency County Hospital Targu Mures, Romania from 2013 to 2020, that included all patients that were diagnosed and surgically operated for gastric adenocarcinoma, Urgent surgery was defined as definitive surgery within 48 hours of admission. Univariate and multivariate analysis of patient factors, surgical outcomes, and oncologic data was performed.

Results: A total of 185 patient data was collected, out of which 107 (57.8%) early interventions and 78 (42.2%) were delayed. With 8 deaths, a total mortality rate of 4.32% was recorded. Postoperative complications were statistically analyzed and no significant correlations were observed in our univariate and multivariate analysis. Moderately positive correlation was observed between total hospital stay and the timeframe between admission and surgery.

Conclusion: In comparison with a delayed elective approach, an early interventional approach showed no significant difference in overall patient survival and surgical outcome in all tested modalities including but not limited to the type of intervention, choice of anastomosis, metastasis and chemotherapy. A positive correlation was observed between the admission to intervention timeframe and total hospital stay.

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